Joshua Ismin
Limited Partner at Possible Ventures
San Francisco Bay Area
Overview
Work Experience
Co-founder, CEO
2021 - Current
Xylo Bio is a pioneering biotech company dedicated to transforming lives with targeted neurotherapeutics. By leveraging advanced neuroscience and a computational drug discovery platform, Xylo is developing neuroplastogens – targeted small molecule therapies designed to rewire neural circuits and restore brain function in patients suffering from psychiatric and neurological disorders. I co-founded the company in 2021 as Psylo, we rebranded to Xylo Bio in 2025 to reflect our sharpened focus on neuroplastogens.
Angel investor and LP
2015
LP in several early stage tech VCs (AirTree, Possible Ventures, Urban Innovation Fund, Better Bite Ventures) and angel investments such as Kanna Health, Finless Foods, Fable Foods, Stockheld Dreamery, Pana Travel (exited), and Clarus Power (shut down).
Founder
2018 - 2022
Facilitated launch of several digital platform businesses in APAC
Co-Founder
2010 - 2017
Internet video business backed by Netus in 2010. Acquired by Tremor Video (now Magnite) as a launchpad for APAC growth.
General Manager, Atlas Asiapac
2008 - 2010
Microsoft Advertising provides digital advertising solutions.
Account Director
2007 - 2008
Part of aQuantive, early ad-serving tech - sold to Microsoft.
E-Marketing Analyst
2005 - 2007
When I was your age online advertising was called E-marketing
International Business Consultant
2004 - 2005
MBA project for St. Louis company with partners in China
Marketing Coordinator
2004 - 2004
6 month internship in Malaysia
Sales Planning Intern
2002 - 2002
First sales planning intern at AOL
AOL Lifestream is a web-based application that enables users to keep track of all their comments on social networking sites.
Raised $1,000,000,000.00 from Comcast Ventures and Google.