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Lorenzo Thione

Managing Director at Gaingels

Chicago, Illinois

Overview 

Lorenzo Thione is a public speaker, investor in artificial intelligence, and Broadway producer based in Chicago, Illinois. He has a strong background in entrepreneurship and data mining, with notable achievements including founding Powerset, Inc. and serving as Managing Director at Gaingels. Thione's career highlights include founding Powerset, Inc. and serving as Managing Director at Gaingels, where he invests in a variety of sectors including artificial intelligence, wellness & fitness, and digital health.

Work Experience 

  • Managing Director

    2019 - Current

    Lead investments in AI, deep tech, and consumer technologies while driving initiatives to increase minority representation in venture capital, shaping the future of ethical AI development. Gaingels is a leading investment syndicate dedicated to balancing minority representation in venture and one of the most active private investors in North America. Gaingels has invested over $300 million in more than 500 LGBTQ+ led companies, and $1B+ across over 2400 startups more broadly.

Gaingels provides funding to startup companies and supports diversity and inclusion within the entrepreneurial ecosystem.

  • Keynote Speaker

    2022

    I have spoken for events and brands including the Central Asia Tech Summit, Tech.Emotion, Iceland Innovation Week, She Angel Investors, and Startup World Cup about various topics, including: • State of the Union: Entrepreneur Funding & Job Creation Without Diversity • The Power of Visibility & Representation in Entrepreneurship • From the Stage to Startups: The Art of Storytelling for Founders • Scaling Opportunities for Diverse Founders • Innovation and Digital Disruption in the Age of AI • What’s Possible: Human Ingenuity and Creativity With AI

  • Managing Partner

    2008

    A theatrical and film production company headquartered in New York City, with shows on Broadway, The West End, and touring and sit down productions around the world : Days of Wine and Roses (2024), The Notebook (2024), &Juliet (2022 Tony Nomination), Mrs Doubtfire (2020), The Inheritance (2020 Tony Award - Best Play), Slave Play (2020 Tony Nomination), Hadestown (2019 Tony Award - Best Musical), Allegiance (2015), Catch Me If You Can (2010 Tony Nomination), American Idiot (2009), Slava Snowshow (2008 Tony Nomination) In addition, Sing Out Louise Productions created and produced the Stage To Screen film adaptations of Allegiance (2016), and Bandstand (2017) Current projects include: Showstopper! on Broadway, a new play Relentless, and two new original musicals, Indigo and Midnight at The Palace.

  • Co-Founder & Chairman Emeritus

    2009

    The leading non-profit committed to supporting and elevating LGBTQ+ founders in the venture startup ecosystem​.

  • Co-Founder & Chairman of The Board

    2013

    The Social Edge is a dynamic social media tech startup that helps digital publishers connect their content with targeted and engaged audiences by harnessing the power of social influencers. The Social Edge's proprietary influencer platform, Contempo, helps each influencers develop and grow their audience by uniquely selecting, testing and targeting syndicated content from our publisher network that is relevant to their audience and their shared interests.

The Social Edge is a social media marketing and consulting firm.

  • Member Board Of Directors

    2017 - 2019

Kenzen’s Mission is to harness the power of physiology data to predict and prevent industrial workforce injuries and improve productivity.

Raised $9,050,000.00 from Examinetics and KCRise Fund.

  • Member Board of Directors

    2014 - 2017

Permission.io is transforming digital advertising by enabling brands and consumers to connect on a permission basis.

Raised $13,368,682.00.

  • Co-Founder, President & Chairman

    2012 - 2014

  • Principal Program Manager, Powerset/Bing

    2008 - 2010

Microsoft Advertising provides digital advertising solutions.

  • Founder & Product Architect

    2006 - 2008

    I started Powerset with an exciting vision to change online search, based on a better understanding of documents and users' intent. In August 2008 Microsoft acquired Powerset with the vision of bringing its team and technologies together to help Microsoft Live Search become the world's best search engine.

Powerset is a search engine focused on in-depth natural language processing.

Raised $20,500,000.00 from Amidzad Partners, Felicis, Founders Fund, CommerceNet, Foundation Capital and Valley Venture Capital.

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