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Rob Hopfner

Managing Partner at Pivotal bioVenture Partners

San Francisco, California

Overview 

Rob Hopfner is a highly accomplished Life Sciences Venture Capital professional based in San Francisco, California, currently serving as Managing Partner at Pivotal bioVenture Partners. With a strong background in venture capital and corporate development, Rob has successfully led investments in notable companies like Evommune and Oculis, contributing to their growth and success in the pharmaceutical and biotech sectors.

Work Experience 

  • Managing Partner

    2017 - Current

    - Life sciences venture capital firm focused on North American and European biotech - Built team and operations, and co-led investment, fundraising, and LP management activities in two biotech venture capital funds totaling $689 million under management Key investments include: - Arcutis Therapeutics (NASDAQ: ARQT), Evommune, Inc, Exscientia, Inc (acquired by Recursion), Gracell Therapeutics (acquired by Astra Zeneca), Karuna Therapeutics (acquired by BMS), Oculis Therapeutics (NASDAQ: OCS), Vaxcyte Therapeutics (NASDAQ: PCVX)

  • Executive Committee Member

    2022

    Oversight of public investment, VC fund investments, and Pivotal bioVenture Partners investment activities

  • Board Member

    2020

Evommune is a biotechnology company that develops therapeutics that halt progressive disease and address their symptoms.

Raised $268,000,000.00 from NEXTBio Capital, RTW Investments, Longwood Fund, RA Capital Management, Sectoral Asset Management, Marshall Wace, Avego Bioscience Capital, SymBiosis, FemHealth Ventures and Andera Partners.

  • Board Member

    2021

Plexium develops a targeted protein degradation platform to find new therapies for cancer and other diseases.

Raised $165,000,000.00 from CRV, RA Capital Management, Pappas Capital, DCVC Bio, SoftBank Vision Fund, Pivotal bioVenture Partners, M Ventures, Surveyor Capital, Lux Capital and Neotribe Ventures.

  • Board Member

    2019

  • Board Member

    2017 - 2023

  • Board Member

    2017 - 2021

Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.

Raised $3,847,040,000.00 from CARB-X and CARB-X.

  • Managing Director and Partner

    2009 - 2017

    Life sciences venture capital firm focused on North American and European biotech Led or co-led 12 investments as a Partner at the firm with top-tier returns and low loss-rate Key investments include: - Civitas Therapeutics (acquired by Acorda), Dermira (acquired by Lilly), Hyperion Therapeutics (acquired by Horizon Pharma), Madrigal Pharmaceuticals (NASDAQ: MDGL), Merus Therapeutics (NASDAQ: MRUS), NextWave Pharmaceuticals (acquired by Pfizer), Protez (acquired by Novartis), Vtesse (acquired by Sucampo), and Zymogenetics (acquired by BMS)

  • Principal

    2006 - 2009

Bay City Capital LLC (Bay City Capital), established in 1997 , specializes in investments in the life sciences industry.

  • Board Member

    2015 - 2017

    Rare disease company acquired by Sucampo Therapeutics

  • Board Member

    2013 - 2014

  • Board Observer

    2010 - 2014

    Dermatology drug development company acquired by Lilly, Inc.

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